Serine

Serine

SCHEMBL359195

N[C@@H](CO)C(=O)O.O=C(O)c1nccs1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
GRIK1 P39086 2/20 0.41
GRIA1 P42261 2/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIK2 Q13002 1/20 0.41
GRIK3 Q13003 1/20 0.41
GRIK4 Q16099 1/20 0.41
GRIK5 Q16478 1/20 0.41
PLA2G4A P47712 1/20 0.38
CES1 P23141 1/20 0.38
SLC1A1 P43005 1/20 0.34
HSD17B10 Q99714 2/20 0.34
SLC7A5 Q01650 1/20 0.34
RBBP9 O75884 1/20 0.34
USP2 O75604 2/20 0.33
ARG1 P05089 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL359193 1.00 ALDH1A1 (0.44) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Cysteine SCHEMBL1986796 0.86 PTGS1 (0.50) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Cysteine SCHEMBL357652 0.86 PTGS1 (0.50) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Phenylalanine SCHEMBL367780 0.81 SLC7A5 (0.61) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Lysine SCHEMBL1983160 0.81 GSR (0.56) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Lysine SCHEMBL358312 0.81 GSR (0.56) ALDH1A1GRIK1GRIA1GRIA2GRIA3
Hydrazine SCHEMBL17745707 0.80 ALDH1A1 (0.59) ALDH1A1PLA2G4ACES1HSD17B10RBBP9
SCHEMBL121301 0.80
SCHEMBL27966320 0.79 ALDH1A1 (0.46) ALDH1A1GRIK1GRIA1GRIA2GRIA3
SCHEMBL27966319 0.79 ALDH1A1 (0.46) ALDH1A1GRIK1GRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992518-B2 Molecular vaccines for infectious disease AGILENT TECHNOLOGIES, INC. (US) 2024-05-28 US disclosed
EP-3334498-B1 METHODS OF TREATING VOLUME DEPLETION AND KIDNEY INJURY UNIV COLUMBIA (US) 2023-06-07 EP disclosed
US-11119104-B2 Methods of treating volume depletion and kidney injury THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2021-09-14 US disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
US-20190314471-A1 MOLECULAR VACCINES FOR INFECTIOUS DISEASE AGILENT TECHNOLOGIES, INC. 2019-10-17 US disclosed
US-10369204-B2 Molecular vaccines for infectious disease DAKO DENMARK A/S (DK) 2019-08-06 US disclosed
EP-3334498-A1 METHODS OF TREATING VOLUME DEPLETION AND KIDNEY INJURY The Trustees of Columbia University in the City of New York (US) 2018-06-20 EP disclosed
WO-2003020897-A2 COMPOSITIONS AND METHODS RELATING TO OVARY SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020934-A1 COMPOSITIONS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020953-A2 COMPOSITIONS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020900-A2 COMPOSITIONS AND METHODS RELATING TO BREAST SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020901-A2 COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
WO-2003020899-A2 COMPOSITIONS AND METHODS RELATING TO LUNG SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
US-20020102610-A1 Automated identification of peptides OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-08-01 US disclosed
US-20020055186-A1 Detection of peptides OXFORD GLYCOSCIENCES (UK) LTD. 2002-05-09 US disclosed
WO-2002025287-A2 DETECTION OF PEPTIDES OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-03-28 WO disclosed
WO-2002021139-A2 AUTOMATED IDENTIFICATION OF PEPTIDES OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-03-14 WO disclosed