SCHEMBL3592430

SCHEMBL3592430

NCCC[CH]C(=O)NC1(C(N)=O)CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TACR2 P21452 1/20 0.31
TACR1 P25103 1/20 0.31
OPRL1 P41146 1/20 0.30
CNR2 P34972 1/20 0.30
CPB2 Q96IY4 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14811587 0.82 SPHK1 (0.30)
SCHEMBL21393151 0.73 TSHR (0.33) TACR2TACR1
SCHEMBL1957150 0.68 KDM4E (0.36) OPRL1CNR2
SCHEMBL3585771 0.68 OPRL1 (0.34) OPRL1
SCHEMBL32690599 0.67 KDM4E (0.39) OPRL1
SCHEMBL13448704 0.66 ALDH1A1 (0.40) OPRL1CNR2
SCHEMBL30389190 0.66 SPHK1 (0.37) TACR2TACR1OPRL1CNR2
SCHEMBL4928521 0.66 KDM4E (0.38) OPRL1
SCHEMBL2847319 0.64 KDM4E (0.41) OPRL1
SCHEMBL20951910 0.64 SIRT6 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed
EP-1885693-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 Wurster, Siegfried (FI) 2008-02-13 EP disclosed
WO-2006123020-A1 PEPTIDOMIMETICS SELECTIVE FOR THE SOMATOSTATIN RECEPTOR SUBTYPES 1 AND/OR 4 JUVANTIA PHARMA LTD OY (FI) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 TACR2 47/4885TACR1 19/4885OPRL1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.