Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824667 | 0.85 | MTNR1A (0.59) | MTNR1APARP1KDM4EALDH1A1DAO | |
| SCHEMBL15485039 | 0.82 | MTNR1A (0.53) | MTNR1APARP1KDM4EALDH1A1KMT2A | |
| SCHEMBL16293902 | 0.80 | HDAC6 (0.41) | MTNR1AKDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL16293127 | 0.78 | HDAC6 (0.40) | MTNR1AKDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL15157126 | 0.78 | KDM4E (0.44) | MTNR1APARP1KDM4EALDH1A1KMT2A | |
| SCHEMBL114693 | 0.78 | MTNR1A (0.57) | MTNR1APARP1KMT2ADAOSLC22A12 | |
| SCHEMBL25526559 | 0.77 | FPR2 (0.41) | KDM4EALDH1A1KMT2AHDAC6FPR2 | |
| SCHEMBL30229742 | 0.77 | KMT2A (0.59) | KDM4EALDH1A1KMT2A | |
| SCHEMBL3597779 | 0.77 | KMT2A (0.59) | KDM4EALDH1A1KMT2A | |
| SCHEMBL28928193 | 0.77 | HDAC6 (0.40) | KDM4EALDH1A1HDAC6FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076632-A1 | COMPOUNDS AND USES THEREOF | FIBROCOR THERAPEUTICS INC. (CA) | 2025-04-17 | — | — | WO | disclosed |
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | MTNR1A 583/4885PARP1 2961/4885KDM4E 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.