Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27633516 | 0.97 | CYP3A4 (0.43) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| SCHEMBL35948 | 0.97 | — | — | |
| Bromide SCHEMBL28098240 | 0.94 | MEN1 (0.45) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| Iodide SCHEMBL5787882 | 0.94 | MEN1 (0.38) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| Sulfuric Acid SCHEMBL5786333 | 0.82 | BBOX1 (0.43) | CYP3A4SLC5A7MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL14957656 | 0.81 | CYP3A4 (0.32) | CYP3A4SLC5A7TSHR | |
| Hydrochloric Acid SCHEMBL31065566 | 0.78 | APEX1 (0.60) | CYP3A4SLC5A7APEX1NPSR1MEN1 | |
| SCHEMBL8049934 | 0.78 | — | — | |
| SCHEMBL14958464 | 0.78 | TSHR (0.32) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL336333 | 0.77 | CYP3A4 (0.41) | CYP3A4SLC5A7APEX1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113320-A | Foaming mixed alcohol/water composition containing structured oxyalkylated siloxane | 埃科莱布美国股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-109052593-A | Preparation method of composite flocculation agent and products thereof and application | 上海纳米技术及应用国家工程研究中心有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-104674601-A | Macromolecular papermaking dry strength agent | HAO YU ADDITION AGENT CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-103045224-B | Preparation method of viscous oil viscosity reducer containing quaternary ammonium salt structure | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-10-01 | — | — | CN | claimed |
| CN-103720712-A | Method for preparing quaternized chitosan nano iodine disinfectant | UNIV SHANGHAI ENG SCIENCE | 2014-04-16 | — | — | CN | claimed |
| CN-103720711-A | Method for preparing amphiphilic chitosan group nano iodine disinfectant | UNIV SHANGHAI ENG SCIENCE | 2014-04-16 | — | — | CN | claimed |
| CN-102604141-B | Method for preparing antibacterial film of quaternarized chitosan iodine complex | UNIV SHANGHAI ENG SCIENCE | 2013-10-30 | — | — | CN | claimed |
| CN-102604141-A | Method for preparing antibacterial film of quaternarized chitosan iodine complex | UNIV SHANGHAI ENG SCIENCE | 2012-07-25 | — | — | CN | claimed |
| CN-101674800-B | Personal care compositions with enhanced fragrance delivery | UNILEVER NV | 2012-07-18 | — | — | CN | claimed |
| CN-101686917-B | Personal care composition with cocoa butter and dihydroxypropyl ammonium salts | UNILEVER NV | 2012-03-21 | — | — | CN | claimed |
| CN-101083974-B | Comprising dihydroxypropyl tris 1-C3Alkyl) ammonium salts for personal care products | UNILEVER NV | 2010-06-16 | — | — | CN | claimed |
| CN-101048199-B | Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts | UNILEVER NV | 2010-05-26 | — | — | CN | claimed |
| CN-101048200-B | Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts | UNILEVER NV | 2010-05-12 | — | — | CN | claimed |
| CN-101686917-A | Personal care composition with cocoa butter and dihydroxypropyl ammonium salts | UNILEVER PLC | 2010-03-31 | — | — | CN | claimed |
| CN-101674800-A | Personal care compositions with enhanced fragrance delivery | UNILEVER PLC | 2010-03-17 | — | — | CN | claimed |
| CN-101663019-A | Enhanced delivery of certain fragrance components from personal care compositions | UNILEVER NV | 2010-03-03 | — | — | CN | claimed |
| CN-101083974-A | Comprising dihydroxypropyl tris 1－C3Alkyl) ammonium salts for personal care products | UNILEVER NV (NL) | 2007-12-05 | — | — | CN | claimed |
| CN-101048125-A | Quaternary ammonium salts as anti-aging actives in personal care compositions | UNILEVER NV (NL) | 2007-10-03 | — | — | CN | claimed |
| CN-101048200-A | Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts | UNILEVER NV (NL) | 2007-10-03 | — | — | CN | claimed |
| CN-101048199-A | Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts | UNILEVER NV (NL) | 2007-10-03 | — | — | CN | claimed |