Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14958464 | 0.97 | TSHR (0.32) | TDP1TSHR | |
| Hydrochloric Acid SCHEMBL28151661 | 0.89 | DNM1 (0.42) | TSHR | |
| SCHEMBL4230927 | 0.86 | DNM1 (0.44) | TSHR | |
| SCHEMBL19227365 | 0.86 | DNM1 (0.44) | CYP3A4SLC5A7TDP1 | |
| Hydrochloric Acid SCHEMBL27958932 | 0.86 | DNM1 (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL29061501 | 0.83 | BBOX1 (0.34) | — | |
| SCHEMBL4228555 | 0.82 | DNM1 (0.40) | TSHR | |
| SCHEMBL4236054 | 0.82 | DNM1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL25270856 | 0.82 | HTT (0.62) | — | |
| Hydrochloric Acid SCHEMBL35930 | 0.81 | CYP3A4 (0.45) | CYP3A4SLC5A7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111345295-B | Traditional Chinese medicine oil modified active silicon antibacterial liquid and preparation method thereof, and preparation method of antibacterial coating | 深圳正海创新材料有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-111345295-A | Traditional Chinese medicine oil modified active silicon antibacterial liquid and preparation method thereof, and preparation method of antibacterial coating | 深圳正海创新材料有限公司 | 2020-06-30 | — | — | CN | claimed |
| US-8648025-B2 | Personal care compositions with silicones and polyhydroxy quaternary ammonium salts | CONOPCO, INC. (US) | 2014-02-11 | — | — | US | claimed |
| US-8496916-B2 | Sunscreen composition with polyhydroxy quaternary ammonium salts | CONOPCO, INC. (US) | 2013-07-30 | — | — | US | claimed |
| WO-2013076147-A2 | PERSONAL CARE COMPOSITIONS WITH SILICONES AND POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | claimed |
| WO-2013076149-A2 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | claimed |
| WO-2013076148-A2 | PERSONAL CARE COMPOSITIONS WITH ENHANCED FRAGRANCE DELIVERY VIA POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | claimed |
| US-20130129644-A1 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | CONOPCO, INC., D/B/A UNILEVER (US) | 2013-05-23 | — | — | US | claimed |
| US-20130129645-A1 | Personal Care Compositions with Silicones and Polyhydroxy Quaternary Ammonium Salts | CONOPCO, INC., D/B/A UNILEVER (US) | 2013-05-23 | — | — | US | claimed |
| CN-111345295-B | Traditional Chinese medicine oil modified active silicon antibacterial liquid and preparation method thereof, and preparation method of antibacterial coating | 深圳正海创新材料有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-111345295-A | Traditional Chinese medicine oil modified active silicon antibacterial liquid and preparation method thereof, and preparation method of antibacterial coating | 深圳正海创新材料有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-104010621-B | Sunscreen composition with polyhydroxy quaternary ammonium salts | 荷兰联合利华有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104010621-A | Sunscreen composition with polyhydroxy quaternary ammonium salts | UNILEVER NV | 2014-08-27 | — | — | CN | disclosed |
| US-8648025-B2 | Personal care compositions with silicones and polyhydroxy quaternary ammonium salts | CONOPCO, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| WO-2013076149-A2 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076149-A2 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013076147-A2 | PERSONAL CARE COMPOSITIONS WITH SILICONES AND POLYHYDROXY QUATERNARY AMMONIUM SALTS | UNILEVER PLC (GB) | 2013-05-30 | — | — | WO | disclosed |
| US-20130129644-A1 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | CONOPCO, INC., D/B/A UNILEVER (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129644-A1 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | CONOPCO, INC., D/B/A UNILEVER (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129645-A1 | Personal Care Compositions with Silicones and Polyhydroxy Quaternary Ammonium Salts | CONOPCO, INC., D/B/A UNILEVER (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129644-A1 | SUNSCREEN COMPOSITION WITH POLYHYDROXY QUATERNARY AMMONIUM SALTS | MMS19, RAD23B, DDAH1 | CYP3A4 3013/4885SLC5A7 4048/4885TDP1 765/4885 |
| US-20130129645-A1 | Personal Care Compositions with Silicones and Polyhydroxy Quaternary Ammonium Salts | CUTA, TAF1, KAT2A | CYP3A4 4291/4885SLC5A7 3610/4885TDP1 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.