Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583365 | 0.85 | MAPT (0.45) | ALDH1A1HTR2AMAPTKDM4EHTT | |
| SCHEMBL13292998 | 0.81 | MEN1 (0.57) | ALDH1A1MAPTHTTL3MBTL1HTR3A | |
| Ammonia Solution, Strong SCHEMBL3580502 | 0.79 | MEN1 (0.55) | ALDH1A1MAPTHTTL3MBTL1HTR3A | |
| SCHEMBL429632 | 0.78 | MAPT (0.62) | ALDH1A1HTR1DHTR1BHTR2AMAPT | |
| SCHEMBL16387109 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HTR1DHTR1BHTR2AMAPT | |
| SCHEMBL25719100 | 0.78 | HTR6 (0.47) | ALDH1A1HTR1DHTR1BHTR2AMAPT | |
| SCHEMBL19403575 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTPOLBHTR1ANPSR1 | |
| SCHEMBL3594190 | 0.77 | DRD2 (0.60) | ALDH1A1HTR1DHTR1BHTR2AKDM4E | |
| SCHEMBL3585035 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTR1DHTR1BHTR2AMAPT | |
| SCHEMBL24243039 | 0.75 | HRH3 (0.46) | ALDH1A1HTR1DHTR1BHTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
| CN-101516888-A | Pyrazolo [1, 5-a] pyrimidine derivatives and their therapeutic use | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | ALDH1A1 4236/4885HTR1D 2359/4885HTR1B 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.