Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 19/20 | 0.86 |
| ▸ | CAPNS1 | P04632 | 16/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3581180 | 0.99 | CAPN1 (0.85) | CAPN1CAPNS1MEN1CYBBAPP | |
| SCHEMBL4537012 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| SCHEMBL3579115 | 0.92 | CAPN1 (0.73) | CAPN1CAPNS1 | |
| SCHEMBL4540146 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| SCHEMBL4532420 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| SCHEMBL4527135 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| SCHEMBL5680223 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| SCHEMBL4538795 | 0.92 | CAPN1 (1.00) | CAPN1CAPNS1 | |
| Iodide SCHEMBL3590734 | 0.92 | CAPN1 (0.72) | CAPN1CAPNS1 | |
| SCHEMBL4622661 | 0.91 | CAPN1 (1.00) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993555-B1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA (FR) | 2012-10-17 | — | — | EP | claimed |
| EP-1954288-B1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | IPSEN PHARMA (FR) | 2012-08-01 | — | — | EP | claimed |
| US-7659266-B2 | Amidine derivatives and their applications as a medicament | S.C.R.A.S. (FR) | 2010-02-09 | — | — | US | claimed |
| US-20090149430-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | US | claimed |
| US-20090018120-A1 | AMIDINE DERIVATIVES AND THEIR APPLICATIONS AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-01-15 | — | — | US | claimed |
| EP-1954288-A1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2008-08-13 | — | — | EP | claimed |
| WO-2007045761-A1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-04-26 | — | — | WO | claimed |
| US-8642591-B2 | Composition containing amidine derivatives or carboxamide derivatives and steroids, as a medicament | IPSEN PHARMA S.A.S. (FR) | 2014-02-04 | — | — | US | disclosed |
| EP-1993555-B1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA (FR) | 2012-10-17 | — | — | EP | disclosed |
| EP-1954288-B1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | IPSEN PHARMA (FR) | 2012-08-01 | — | — | EP | disclosed |
| US-7659266-B2 | Amidine derivatives and their applications as a medicament | S.C.R.A.S. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20090149430-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | US | disclosed |
| US-20090018120-A1 | AMIDINE DERIVATIVES AND THEIR APPLICATIONS AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-01-15 | — | — | US | disclosed |
| EP-1993555-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS (FR) | 2008-11-26 | — | — | EP | disclosed |
| EP-1954288-A1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007101937-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007045761-A1 | AMIDINE DERIVATIVES AND THEIR USES AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149430-A1 | COMPOSITION CONTAINING AMIDINE DERIVATIVES OR CARBOXAMIDE DERIVATIVES AND STEROIDS, AS A MEDICAMENT | MC2R, CYP11B2, NR3C2 | CAPN1 1976/4885CAPNS1 2160/4885MEN1 61/4885 |
| US-20090018120-A1 | AMIDINE DERIVATIVES AND THEIR APPLICATIONS AS A MEDICAMENT | CAPN2, CAPN9, CAPN1 | CAPN1 3/4885CAPNS1 4/4885MEN1 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.