Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486754 | 0.84 | ACE (0.40) | DDB1CRBNALDH1A1HTR5ACREBBP | |
| SCHEMBL7565031 | 0.81 | CASP3 (0.43) | CREBBPBRD4PARP1 | |
| SCHEMBL7479107 | 0.78 | RAB9A (0.46) | ALDH1A1MAPT | |
| SCHEMBL7836971 | 0.77 | CREBBP (0.46) | DDB1CRBNALDH1A1HTR5ACREBBP | |
| SCHEMBL3593980 | 0.77 | HTR5A (0.35) | DDB1CRBNHTR5ACREBBPBRD4 | |
| SCHEMBL1450613 | 0.75 | PARP1 (0.36) | DDB1CRBNALDH1A1HTR5ACREBBP | |
| SCHEMBL3591908 | 0.74 | CREBBP (0.38) | DDB1CRBNALDH1A1CREBBPBRD4 | |
| SCHEMBL27746212 | 0.73 | PARP1 (0.37) | DDB1CRBNALDH1A1HTR5ACREBBP | |
| SCHEMBL7826445 | 0.73 | CA9 (0.43) | DDB1CRBNHTR5AMAPT | |
| SCHEMBL3592386 | 0.73 | TRPV1 (0.38) | DDB1CRBNALDH1A1HTR5ACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |