Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593971 | 0.89 | TRPV1 (0.38) | HTR1ADRD2DRD3CRBNDDB1 | |
| SCHEMBL3594033 | 0.86 | TRPV1 (0.40) | HTR1ADRD2DRD3CRBNDDB1 | |
| SCHEMBL3596677 | 0.84 | CRBN (0.33) | HTR1ADRD2DRD3CRBNDDB1 | |
| SCHEMBL3599588 | 0.80 | HTR1A (0.36) | HTR1ADRD2DRD3 | |
| SCHEMBL3598950 | 0.80 | ALDH1A1 (0.34) | HTR1ADRD2DRD3CRBNDDB1 | |
| SCHEMBL3597335 | 0.76 | CRBN (0.37) | HTR1ADRD2DRD3CRBNDDB1 | |
| SCHEMBL3600259 | 0.74 | CA9 (0.33) | CRBNDDB1 | |
| SCHEMBL3588367 | 0.74 | CA9 (0.41) | CRBNDDB1 | |
| SCHEMBL3593970 | 0.73 | TRPV1 (0.38) | DRD2DRD3CRBNDDB1 | |
| SCHEMBL14550569 | 0.73 | ACHE (0.40) | DRD2CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | HTR1A 1118/4885DRD2 530/4885DRD3 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.