Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580905 | 0.98 | TGM2 (0.41) | HTTLMNASMN1; SMN2TGM2IDO1 | |
| SCHEMBL3586429 | 0.94 | SMN1; SMN2 (0.41) | HTTLMNASMN1; SMN2TGM2IDO1 | |
| SCHEMBL3585846 | 0.89 | POLB (0.41) | LMNASMN1; SMN2IDO1POLBMAPT | |
| SCHEMBL27928158 | 0.75 | RIPK1 (0.50) | LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL3584000 | 0.74 | CYP2C9 (0.42) | LMNASMN1; SMN2IDO1MAPTL3MBTL1 | |
| SCHEMBL13622021 | 0.73 | IDO1 (0.56) | HTTLMNASMN1; SMN2IDO1POLB | |
| SCHEMBL3590061 | 0.72 | SCN9A (0.38) | SMN1; SMN2 | |
| SCHEMBL20196937 | 0.71 | L3MBTL1 (0.58) | LMNASMN1; SMN2IDO1POLBMAPT | |
| SCHEMBL3580353 | 0.70 | MEN1 (0.53) | IDO1POLBMAPTCTSSSIGMAR1 | |
| SCHEMBL506649 | 0.70 | IDO1 (0.62) | HTTLMNASMN1; SMN2IDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | Wurster, Siegfried (FI) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | SSTR1, SSTR4, SSTR3 | HTT 1383/4885LMNA 4415/4885SMN1; SMN2 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.