Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10517128 | 0.98 | ALDH1A1 (0.97) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL4018329 | 0.91 | ALDH1A1 (0.83) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL3417681 | 0.88 | ALDH1A1 (0.78) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL9370578 | 0.88 | ALDH1A1 (0.78) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL4016994 | 0.87 | ALDH1A1 (0.76) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL3171933 | 0.86 | SMN1; SMN2 (1.00) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL13207381 | 0.85 | ALDH1A1 (0.74) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL14291480 | 0.84 | MEN1 (0.73) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL14426616 | 0.84 | MEN1 (1.00) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 | |
| SCHEMBL7010784 | 0.84 | ALDH1A1 (0.72) | ALDH1A1CYP2C9SMN1; SMN2TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | claimed |
| US-20080139817-A1 | Process For Producing 2-(Phenyl Methyl Thio)-3-Pyridine Carboxylic Acid | JUBILANT ORGANOSYS LIMITED (IN) | 2008-06-12 | — | — | US | claimed |
| WO-2005097748-A1 | PROCESS FOR PRODUCING 2-(PHENYL METHYL THIO)-3-PYRIDINE CARBOXYLIC ACID | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-20 | — | — | WO | claimed |
| CN-106928134-B | A kind of preparation facilities and synthetic method of nicosulfuron intermediate | 山东理工大学 | 2019-07-16 | — | — | CN | disclosed |
| US-9340505-B2 | Type III secretion inhibitors, analogs and uses thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2016-05-17 | — | — | US | disclosed |
| US-20140323483-A1 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2014-10-30 | — | — | US | disclosed |
| US-20110034463-A1 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-10 | — | — | US | disclosed |
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | disclosed |
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | disclosed |
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | disclosed |
| US-20080139817-A1 | Process For Producing 2-(Phenyl Methyl Thio)-3-Pyridine Carboxylic Acid | JUBILANT ORGANOSYS LIMITED (IN) | 2008-06-12 | — | — | US | disclosed |
| WO-2005097748-A1 | PROCESS FOR PRODUCING 2-(PHENYL METHYL THIO)-3-PYRIDINE CARBOXYLIC ACID | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-20 | — | — | WO | disclosed |
| EP-0237292-B1 | Herbicidal pyridine sulfonamides | DU PONT (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0547035-A1 | Pyridinecarboxamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5008393-A | Kills grasses, safe for corn; pre- and postemergence | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0314302-A2 | Herbicidal o-carbomethoxy-sulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-05-03 | — | — | EP | disclosed |
| WO-1989002700-A2 | HERBICIDAL O-CARBOMETHOXYSULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-06 | — | — | WO | disclosed |
| US-4789393-A | SAFE TO CORN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| US-4786734-A | FOR GRASSES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0237292-A2 | Herbicidal pyridine sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034463-A1 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF | GBA3, CLPP, PEX3 | ALDH1A1 4877/4885CYP2C9 4055/4885SMN1; SMN2 4655/4885 |
| US-20140323483-A1 | TYPE III SECRETION INHIBITORS, ANALOGS AND USES THEREOF | GBA3, CLPP, PEX3 | ALDH1A1 4877/4885CYP2C9 4055/4885SMN1; SMN2 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.