Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594763 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10517128 | 0.82 | ALDH1A1 (0.97) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL9370578 | 0.81 | ALDH1A1 (0.78) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL8630241 | 0.81 | L3MBTL1 (1.00) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL9363791 | 0.80 | PPARG (0.46) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL8931159 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL13207381 | 0.79 | ALDH1A1 (0.74) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL9571741 | 0.79 | DDB1 (0.53) | ALDH1A1CYP2C9L3MBTL1SMN1; SMN2TP53 | |
| SCHEMBL9364221 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 | |
| SCHEMBL13242893 | 0.78 | L3MBTL1 (0.76) | ALDH1A1CYP2C9L3MBTL1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547035-A1 | Pyridinecarboxamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | disclosed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |
| EP-0388994-B1 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0232067-B2 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0237292-B1 | Herbicidal pyridine sulfonamides | DU PONT (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0547035-A1 | Pyridinecarboxamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5008393-A | Kills grasses, safe for corn; pre- and postemergence | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0388994-A1 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4789393-A | SAFE TO CORN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| US-4786734-A | FOR GRASSES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0237292-A2 | Herbicidal pyridine sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| EP-0232067-A2 | Substituted pyridinesulfonamide compounds, herbicidal composition containing them, and method of preparing these compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1987-08-12 | — | — | EP | disclosed |