SCHEMBL3595215

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3491789	0.90	TLR8 (0.38)	TLR8TLR7ITKATRPDE2A
	SCHEMBL3494352	0.88	PDE2A (0.37)	TLR8TLR7ITKROCK2ROCK1
	SCHEMBL3603844	0.85	ATR (0.45)	TLR8TLR7ITKATRROCK2
	SCHEMBL1723378	0.85	KDM4E (0.52)	TLR8TLR7ITKATRROCK2
	SCHEMBL3589339	0.82	TLR8 (0.43)	TLR8TLR7ITKPDE2APDE6D
	SCHEMBL3583521	0.82	TLR8 (0.43)	TLR8TLR7ITKROCK2ROCK1
	SCHEMBL11997342	0.82	TLR8 (0.42)	TLR8TLR7ITKMAPK1PDE2A
	SCHEMBL3589144	0.82	TLR8 (0.42)	TLR8TLR7ITKMAPK1PDE2A
	SCHEMBL3591362	0.81	PDE2A (0.46)	AURKAPDE2APDE6DPDE8APDE5A
	SCHEMBL3595214	0.81	TLR8 (0.42)	TLR8TLR7ITKPDE2APDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.