SCHEMBL3595214

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3491787	0.90	PDE9A (0.38)	TLR8TLR7PDE9AHTR7KMT2A
	SCHEMBL3494351	0.89	PDE9A (0.38)	TLR8TLR7PDE9AKMT2APOLB
	SCHEMBL3603839	0.85	PDE9A (0.59)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL1723377	0.85	PDE9A (0.42)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL11997315	0.85	ALDH1A1 (0.42)	PDE9AITKKMT2AKDM4EALDH1A1
	SCHEMBL11997342	0.84	TLR8 (0.42)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL3589144	0.84	TLR8 (0.42)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL3591785	0.84	PDE9A (0.57)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL3589339	0.83	TLR8 (0.43)	TLR8TLR7PDE9AITKHTR7
	SCHEMBL3591359	0.82	L3MBTL1 (0.43)	PDE9AKMT2APOLBMEN1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.