Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.54 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447481 | 1.00 | KCNQ3 (0.54) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL3447133 | 0.89 | MAPT (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL3446563 | 0.87 | PNMT (0.57) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL14393693 | 0.87 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL14393696 | 0.87 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| Hydrochloric Acid SCHEMBL168310 | 0.86 | PNMT (0.56) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL3447393 | 0.86 | SLC6A9 (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL14368095 | 0.85 | HDAC1 (0.52) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL18162789 | 0.85 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 | |
| SCHEMBL16901653 | 0.85 | KCNQ2 (0.49) | KCNQ3KCNQ2KCNQ4KCNQ5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431607-B2 | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2013-04-30 | — | — | US | disclosed |
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234365-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | KCNQ3 1193/4885KCNQ2 1154/4885KCNQ4 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.