Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371135 | 0.88 | MAPT (0.42) | CA12CA2CA9CA1SMN1; SMN2 | |
| SCHEMBL10340643 | 0.76 | ALDH1A1 (0.55) | CA12CA9SMN1; SMN2LMNAHPGD | |
| SCHEMBL20028196 | 0.76 | MAPT (0.55) | SMN1; SMN2LMNAGAAHPGDMEN1 | |
| SCHEMBL22897266 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAGAAHPGDMEN1 | |
| SCHEMBL20554113 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAGAAHPGDMEN1 | |
| SCHEMBL360852 | 0.71 | MAPT (0.58) | CA12CA2CA9CA1SMN1; SMN2 | |
| SCHEMBL1509460 | 0.69 | ALDH1A1 (0.51) | CA12CA9SMN1; SMN2LMNAHPGD | |
| SCHEMBL8357021 | 0.69 | ALDH1A1 (0.61) | CA12CA2CA9SMN1; SMN2LMNA | |
| SCHEMBL369164 | 0.69 | ALDH1A1 (0.48) | CA12CA9SMN1; SMN2LMNAGAA | |
| SCHEMBL2079861 | 0.68 | NPSR1 (0.64) | CA12CA9SMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |