Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359720 | 0.88 | CA12 (0.50) | MAPTCA2CA1TP53CYP3A4 | |
| SCHEMBL1848550 | 0.68 | CYP3A4 (0.68) | MAPTCA2CA1TP53HSD17B10 | |
| SCHEMBL15062756 | 0.68 | CYP3A4 (0.64) | MAPTCA2CA1TP53HSD17B10 | |
| SCHEMBL20367013 | 0.68 | RAB9A (0.63) | MAPTCA2CA1ALDH1A1CA12 | |
| SCHEMBL2079861 | 0.67 | NPSR1 (0.64) | MAPTTP53HSD17B10ALDH1A1CA12 | |
| SCHEMBL10340643 | 0.67 | ALDH1A1 (0.55) | MAPTTP53HSD17B10ALDH1A1CA12 | |
| SCHEMBL3348202 | 0.66 | LMNA (0.62) | MAPTTP53HSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL13805532 | 0.65 | SMN1; SMN2 (0.51) | MAPTCA2CA1TP53HSD17B10 | |
| SCHEMBL28548123 | 0.65 | MAPK1 (0.41) | MAPTTP53HSD17B10ALDH1A1CA12 | |
| SCHEMBL3720342 | 0.65 | NPC1 (0.46) | MAPTTP53HSD17B10ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |