Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.45 |
| ▸ | ILK | Q13418 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360263 | 0.81 | RAB9A (0.55) | MAPTCYP1A2CYP3A4CYP2C19APP | |
| SCHEMBL359189 | 0.80 | HTT (0.54) | MAPTAPPNPC1RAB9ATP53 | |
| SCHEMBL12505621 | 0.80 | RAB9A (0.38) | MAPTTSHRAPPNPC1RAB9A | |
| SCHEMBL29683488 | 0.74 | CYP3A4 (1.00) | MAPTTSHRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22358 | 0.74 | CYP3A4 (1.00) | MAPTTSHRCYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL11423357 | 0.72 | CYP3A4 (0.97) | MAPTTSHRCYP1A2CYP3A4CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL7998249 | 0.72 | CYP3A4 (0.97) | MAPTTSHRCYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL11151690 | 0.72 | CYP3A4 (0.97) | MAPTTSHRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL371310 | 0.71 | CA1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL3468767 | 0.70 | MAPT (0.65) | MAPTTSHRCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |