SCHEMBL359722

SCHEMBL359722

C#CCc1ccc(CO)o1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 2/20 0.42
KDM4E B2RXH2 4/20 0.35
MAPT P10636 2/20 0.35
CYP2A6 P11509 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CYP2C19 P33261 2/20 0.30
NPC1 O15118 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
G6PC1 P35575 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183551 0.80
SCHEMBL15978557 0.77 MEN1 (0.33) ALDH1A1SMN1; SMN2NPC1RAB9AG6PC1
SCHEMBL11841928 0.77
SCHEMBL9569265 0.73
SCHEMBL9228013 0.73
SCHEMBL852252 0.73
SCHEMBL584774 0.73
SCHEMBL15977349 0.72 NPC1 (0.33) TSHRNPC1CYP1A2RAB9AL3MBTL1
SCHEMBL9569293 0.72 L3MBTL1 (0.32) ALDH1A1TDP1KDM4EL3MBTL1
SCHEMBL901053 0.72 ALDH1A1 (0.50) ALDH1A1TDP1TSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP claimed
US-7741511-B2 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US claimed
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS SOUDA HIROSHI 2008-01-10 US claimed
EP-1792889-A2 Process for the preparation of carboxylic acid esters Sumitomo Chemical Company, Limited (JP) 2007-06-06 EP claimed
CN-1660764-A Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2005-08-31 CN claimed
EP-1547995-A1 Process for the preparation of carboxylic acid esters Sumitomo Chemical Company, Limited (JP) 2005-06-29 EP claimed
US-20050113581-A1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL COMPANY, LIMITED 2005-05-26 US claimed
JP-55069571-A None JP disclosed
CN-102762532-B The manufacture method of cyano group alkenyl cyclopropanecarboxylic acid salt SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-07-29 CN disclosed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP disclosed
CN-102365264-B Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL CO 2014-05-21 CN disclosed
EP-1547995-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
US-4113968-A FROM A 1-HALO-3-ALKENE-2-OL KURARAY CO., LTD. (JP) 1978-09-12 US disclosed
US-3998868-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-12-21 US disclosed
US-3992526-A 5-Ethoxymethyl furfuryl ester of chrysanthemumic acid and its use as an insecticide DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JA) 1976-11-16 US disclosed
US-3982013-A INSECTICIDES DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JA) 1976-09-21 US disclosed
US-3968238-A INSECTICIDE DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JA) 1976-07-06 US disclosed
US-3954814-A INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US disclosed
US-3932470-A INSECTICIDES DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113581-A1 Process for the preparation of carboxylic acid esters ACSL6, ALKBH3, ACSL1 ALDH1A1 184/4885TDP1 4138/4885TSHR 1811/4885
US-20080009648-A1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS ACSL6, ALKBH3, ACSL1 ALDH1A1 184/4885TDP1 4138/4885TSHR 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.