SCHEMBL9569293

SCHEMBL9569293

C#CCc1ccc(COC)o1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
PDE5A O76074 1/20 0.31
LMNA P02545 2/20 0.31
RECQL P46063 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55096 0.82 DAO (0.38) L3MBTL1PDE5ALMNARECQLKDM4E
SCHEMBL15978557 0.77 MEN1 (0.33) LMNAALDH1A1
SCHEMBL21115270 0.76 PDE5A (0.31) PDE5ADAO
SCHEMBL27373830 0.76
SCHEMBL19049630 0.74 ALOX5 (0.40) L3MBTL1PDE5ALMNAKDM4EALDH1A1
SCHEMBL18295081 0.72 PDE5A (0.33) L3MBTL1PDE5ALMNARECQLKDM4E
SCHEMBL687459 0.72 ALDH1A1 (0.42) L3MBTL1PDE5ALMNAKDM4EALDH1A1
SCHEMBL18294965 0.72 PDE5A (0.33) L3MBTL1PDE5ALMNAKDM4EALDH1A1
SCHEMBL852252 0.72
SCHEMBL359722 0.72 ALDH1A1 (0.42) L3MBTL1KDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0555153-A1 Pyrethrinoide esters, derivatives of furan- or thiophenalcohol, process for their preparation and application thereof as pesticides ROUSSEL UCLAF (FR) 1993-08-11 EP disclosed