Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208547 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL27581491 | 0.81 | MAPT (0.56) | ALDH1A1MAPTKDM4EGAAKMT2A | |
| SCHEMBL3593153 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL99032 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL27581495 | 0.79 | ADRB1 (0.58) | ALDH1A1KDM4EMAOBSIRT6NCF1 | |
| SCHEMBL22579268 | 0.78 | ALDH1A1 (0.89) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL7995290 | 0.77 | ALDH1A1 (0.86) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL178275 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| SCHEMBL28260866 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4EGAAADRA2C | |
| Water SCHEMBL28942638 | 0.75 | ALDH1A1 (0.83) | ALDH1A1MAPTKDM4EGAAADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | ALDH1A1 4236/4885MAPT 2260/4885KDM4E 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.