Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260866 | 0.94 | ALDH1A1 (0.62) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| SCHEMBL628551 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| Fluorobenzene SCHEMBL28062776 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| SCHEMBL3593153 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| SCHEMBL98716 | 0.83 | TRIM24 (0.63) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL208547 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| SCHEMBL817331 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL609198 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL3597242 | 0.80 | ALDH1A1 (0.70) | ALDH1A1MAPTGAAKDM4EPTK2B | |
| SCHEMBL28072002 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAKDM4EPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213066-A1 | Hairy Polymeric Nanoparticles With First And Second Shell Block Polymer Arms | BRIDGESTONE CORPORATION (JP) | 2011-09-01 | — | — | US | claimed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-9493601-B2 | Hairy polymeric nanoparticles with first and second shell block polymer arms | BRIDGESTONE CORPORATION (JP) | 2016-11-15 | — | — | US | disclosed |
| US-9493601-B2 | Hairy polymeric nanoparticles with first and second shell block polymer arms | BRIDGESTONE CORPORATION (JP) | 2016-11-15 | — | — | US | disclosed |
| US-9493601-B2 | Hairy polymeric nanoparticles with first and second shell block polymer arms | BRIDGESTONE CORPORATION (JP) | 2016-11-15 | — | — | US | disclosed |
| US-9260540-B1 | Method of making a functionalized polymer with sulfide linkage | BRIDGESTONE CORPORATION (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9260540-B1 | Method of making a functionalized polymer with sulfide linkage | BRIDGESTONE CORPORATION (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9221923-B2 | Coupled polymers and methods for making same | BRIDGESTONE CORPORATION (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221923-B2 | Coupled polymers and methods for making same | BRIDGESTONE CORPORATION (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20150291719-A1 | HAIRY POLYMERIC NANOPARTICLES WITH FIRST AND SECOND SHELL BLOCK POLYMER ARMS | BRIDGESTONE CORPORATION (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20130274408-A1 | Coupled Polymers And Methods For Making Same | BRIDGESTONE CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |
| US-20130035443-A1 | METHOD OF MAKING A BLOCKED POLYMER WITH A SILOXANE LINKING GROUP | BRIDGESTONE CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20130035443-A1 | METHOD OF MAKING A BLOCKED POLYMER WITH A SILOXANE LINKING GROUP | BRIDGESTONE CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20120059113-A1 | PROCESSING OF RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS | BRIDGESTONE CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059113-A1 | PROCESSING OF RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS | BRIDGESTONE CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-8012979-B2 | Compounds and their uses 707 | ASTRAZENECA AB (SE) | 2011-09-06 | — | — | US | disclosed |
| US-20110213066-A1 | Hairy Polymeric Nanoparticles With First And Second Shell Block Polymer Arms | BRIDGESTONE CORPORATION (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213066-A1 | Hairy Polymeric Nanoparticles With First And Second Shell Block Polymer Arms | BRIDGESTONE CORPORATION (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213066-A1 | Hairy Polymeric Nanoparticles With First And Second Shell Block Polymer Arms | BRIDGESTONE CORPORATION (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20090023746-A1 | COMPOUNDS AND THEIR USES 707 | ASTRAZENECA AB (SE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023746-A1 | COMPOUNDS AND THEIR USES 707 | CYP3A7, UGT1A7, UGT2B7 | ALDH1A1 272/4885MAPT 1419/4885GAA 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.