Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597424 | 0.83 | TSHR (0.41) | RAB9ASMN1; SMN2MAPTTSHRL3MBTL1 | |
| SCHEMBL3602594 | 0.81 | TSHR (0.57) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF | |
| SCHEMBL3198672 | 0.74 | ATM (0.49) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF | |
| SCHEMBL3603706 | 0.73 | KMO (0.46) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF | |
| SCHEMBL13115635 | 0.73 | KMO (0.43) | ALDH1A1MAPTMDM2KDM4EPOLB | |
| SCHEMBL3203584 | 0.72 | NPSR1 (0.64) | ALDH1A1MAPTHTTTSHRALOX15 | |
| SCHEMBL3200380 | 0.72 | LMNA (0.45) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF | |
| SCHEMBL3193908 | 0.72 | HDAC6 (0.41) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF | |
| SCHEMBL3596889 | 0.71 | HTT (0.66) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL3193840 | 0.71 | MAPT (0.44) | ALDH1A1RAB9ASMN1; SMN2LMNAMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807704-B2 | Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2 | CHEMOCENTRYX, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20070275965-A1 | CXCR4 modulators | CHEMOCENTRYX, INC. (US) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275965-A1 | CXCR4 modulators | CXCL12, CXCR4, CXCR1 | ALDH1A1 662/4885RAB9A 602/4885SMN1; SMN2 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.