Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | PYGM | P11217 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597598 | 1.00 | GHSR (0.59) | GHSRKDM5AKDM4EHSD17B10HRH4 | |
| SCHEMBL30175947 | 0.85 | HRH4 (0.59) | KDM5AKDM4EHSD17B10HRH4CHRNA7 | |
| SCHEMBL4130958 | 0.84 | CCKBR (0.54) | KDM5AKDM4EHSD17B10CHRNA7HTR3A | |
| SCHEMBL75198 | 0.84 | MLLT1 (0.65) | KDM4EHSD17B10CHRNA7HTR3AMLLT1 | |
| SCHEMBL76132 | 0.84 | MLLT1 (0.69) | KDM4EHSD17B10CHRNA7HTR3AMLLT1 | |
| SCHEMBL3604732 | 0.84 | GHSR (0.49) | GHSRKDM5AKDM4EHSD17B10MLLT1 | |
| SCHEMBL3604730 | 0.84 | GHSR (0.49) | GHSRKDM5AKDM4EHSD17B10MLLT1 | |
| SCHEMBL74832 | 0.82 | MLLT1 (0.67) | KDM4EHSD17B10CHRNA7HTR3AMLLT1 | |
| SCHEMBL74244 | 0.82 | MLLT1 (0.67) | KDM4EHSD17B10CHRNA7HTR3AMLLT1 | |
| SCHEMBL19837645 | 0.82 | MLLT1 (0.67) | KDM4EHSD17B10CHRNA7HTR3AMLLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | US | claimed |
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035862-A1 | NOVEL AZA-CYCLIC INDOLE-2-CARBOXAMIDES AND METHODS OF USE THEREOF | IDO2, IDO1, INMT | GHSR 2639/4885KDM5A 347/4885KDM4E 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.