Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.53 |
| ▸ | CSF1R | P07333 | 8/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359919 | 0.77 | — | — | |
| SCHEMBL30790323 | 0.77 | — | — | |
| SCHEMBL2749680 | 0.76 | NUDT1 (0.51) | NUDT1 | |
| SCHEMBL28120128 | 0.76 | CYP11B1 (0.40) | CSF1RNTRK1NTRK2 | |
| SCHEMBL1034474 | 0.74 | NUDT1 (0.55) | NUDT1 | |
| SCHEMBL4387841 | 0.74 | IDO1 (0.52) | CSF1R | |
| SCHEMBL1257274 | 0.73 | KDM1A (0.43) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL11036646 | 0.73 | NUDT1 (0.65) | NUDT1CCNT1CDK9 | |
| SCHEMBL30228073 | 0.73 | KDM1A (0.43) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21327634 | 0.73 | HSD17B1 (0.43) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593451-B1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8975265-B2 | Substituted imidazo[1,2-a]pyrimidines and —pyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-10 | — | — | US | disclosed |
| US-20130190332-A1 | Substituted Imidazo[1,2-a]pyrimidines and -pyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-25 | — | — | US | disclosed |
| EP-2593451-A2 | SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES | Bayer Intellectual Property GmbH (DE) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007345-A2 | SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190332-A1 | Substituted Imidazo[1,2-a]pyrimidines and -pyridines | PIK3CA, PIK3CD, PIK3CB | NUDT1 503/4885CSF1R 1269/4885DYRK3 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.