Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598381 | 0.88 | DPP4 (0.49) | DPP4CYP3A4DPP8OPRM1OPRK1 | |
| SCHEMBL3079559 | 0.84 | DPP4 (0.51) | DPP4CYP3A4DPP8DPP9CNR1 | |
| SCHEMBL3597097 | 0.82 | DPP4 (0.45) | DPP4CYP3A4DPP8CYP2C19 | |
| SCHEMBL3604955 | 0.81 | DPP4 (0.48) | DPP4CYP3A4DPP8DPP9CNR1 | |
| SCHEMBL3595249 | 0.80 | DPP4 (0.47) | DPP4CYP3A4DPP8DPP9CYP2C19 | |
| SCHEMBL3596963 | 0.80 | DPP4 (0.58) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL4660649 | 0.80 | DPP4 (0.48) | DPP4CYP3A4DPP8 | |
| SCHEMBL3084580 | 0.80 | DPP4 (0.49) | DPP4CYP3A4DPP8CNR1 | |
| SCHEMBL3585733 | 0.79 | DPP4 (0.46) | DPP4CYP3A4DPP8DPP9CNR1 | |
| SCHEMBL3601689 | 0.79 | DPP4 (0.46) | DPP4CYP3A4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |