SCHEMBL3598649

SCHEMBL3598649

CCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)Oc1cc(Br)cc(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.32
PLA2G10 O15496 1/20 0.32
PLA2G1B P04054 1/20 0.32
PLA2G5 P39877 1/20 0.32
ACSS2 Q9NR19 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3601252 0.86 GCK (0.31)
SCHEMBL3599418 0.83
SCHEMBL3607194 0.83 KMT2A (0.35)
SCHEMBL3598854 0.81 MAOB (0.39)
SCHEMBL3599409 0.79 ACACB (0.36)
SCHEMBL27681485 0.77 LMNA (0.33)
SCHEMBL25244010 0.75 PLA2G2A (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL30825799 0.75 PLA2G2A (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL29193316 0.75 PLA2G2A (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL25289028 0.75 PLA2G2A (0.38) PLA2G2APLA2G10PLA2G1BPLA2G5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700640-B2 Process for making phenoxy benzamide compounds ASTRAZENECA AB (SE) 2010-04-20 US disclosed
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds ASTRAZENECA AB (SE) 2008-08-21 US disclosed
EP-1802570-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS AstraZeneca AB (SE) 2007-07-04 EP disclosed
WO-2006040527-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS ASTRAZENECA AB (SE) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds PAH, MAOB, TYR PLA2G2A 3616/4885PLA2G10 4121/4885PLA2G1B 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.