SCHEMBL3607194

SCHEMBL3607194

CCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)Oc1cc(Br)cc(C(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
CYP2C9 P11712 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3594161 0.87 GCK (0.40) KMT2AMEN1NPC1POLBCYP2C9
SCHEMBL3603264 0.84 PLA2G2A (0.35) KMT2AMEN1NPC1POLBCYP2C9
SCHEMBL3598649 0.83 PLA2G2A (0.32)
SCHEMBL3586994 0.80 MEN1 (0.47) KMT2AMEN1MRGPRX4
SCHEMBL3605126 0.80 PLA2G2A (0.40) KMT2AMEN1KDM4EL3MBTL1
SCHEMBL3605804 0.74 PLA2G2A (0.35) KMT2AMEN1NPC1POLBRAB9A
SCHEMBL17060024 0.72 PLA2G2A (0.46) KMT2AMEN1CYP2C9KDM4E
SCHEMBL10941156 0.71 KCNN4 (0.40)
SCHEMBL3592397 0.70 KMT2A (0.45) KMT2AMEN1NPC1RAB9A
SCHEMBL3595570 0.70 GCK (0.37) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700640-B2 Process for making phenoxy benzamide compounds ASTRAZENECA AB (SE) 2010-04-20 US disclosed
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds ASTRAZENECA AB (SE) 2008-08-21 US disclosed
EP-1802570-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS AstraZeneca AB (SE) 2007-07-04 EP disclosed
WO-2006040527-A1 PROCESS FOR MAKING PHENOXY BENZAMIDE COMPOUNDS ASTRAZENECA AB (SE) 2006-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200694-A1 Process for Making Phenoxy Benzamide Compounds PAH, MAOB, TYR KMT2A 726/4885MEN1 2346/4885NPC1 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.