SCHEMBL3598769

SCHEMBL3598769

O=[N+]([O-])c1cccc2ccn(Cc3ccccc3)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.49
HSP90AA1 P07900 1/20 0.49
RECQL P46063 1/20 0.48
APP P05067 3/20 0.47
ALDH1A1 P00352 5/20 0.44
CCR2 P41597 1/20 0.44
SNCA P37840 2/20 0.43
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
CFTR P13569 1/20 0.41
MAPK1 P28482 1/20 0.40
PLA2G2A P14555 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FGFR1 P11362 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6087453 0.89 RECQL (0.49) NPC1HSP90AA1RECQLALDH1A1CCR2
SCHEMBL15845476 0.80 CFTR (0.43) NPC1HSP90AA1RECQLAPPALDH1A1
SCHEMBL24130455 0.80 ALDH1A1 (0.43) RECQLALDH1A1MAPTGAAMEN1
SCHEMBL2875153 0.79 KMT2A (0.50) ALDH1A1CCR2MAPTL3MBTL1MEN1
SCHEMBL2875151 0.79 KMT2A (0.50) ALDH1A1CCR2MAPTL3MBTL1MEN1
SCHEMBL15845448 0.77 RECQL (0.49) NPC1HSP90AA1RECQLALDH1A1CCR2
SCHEMBL15845658 0.76 ALDH1A1 (0.44) NPC1HSP90AA1RECQLALDH1A1CCR2
SCHEMBL13139569 0.75 ALDH1A1 (0.44) ALDH1A1CCR2POLBMAPTL3MBTL1
SCHEMBL31347625 0.75 TXNRD1 (0.42) NPC1ALDH1A1POLBMAPTHTT
SCHEMBL25293342 0.74 RECQL (0.51) RECQLALDH1A1CCR2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103059065-B Azo metal complex and preparation method thereof SHANGHAI TOYOU DIGITAL TECH CO LTD 2015-04-22 CN claimed
US-12037636-B2 Polynucleotide synthesis method, kit and system OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-07-16 US disclosed
US-20220396818-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-15 US disclosed
US-20220213537-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-07-07 US disclosed
US-20220177937-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-06-09 US disclosed
US-20220177938-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-06-09 US disclosed
US-20210388432-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-12-16 US disclosed
US-20210324436-A1 METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-10-21 US disclosed
US-20210198710-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, SYSTEM AND KIT OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-07-01 US disclosed
US-10927394-B2 Methods and reagents for synthesising polynucleotide molecules OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-02-23 US disclosed
WO-2020016606-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2020-01-23 WO disclosed
WO-2020016605-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2020-01-23 WO disclosed
WO-2020016604-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2020-01-23 WO disclosed
US-20190352687-A1 METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-11-21 US disclosed
WO-2019150134-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-08-08 WO disclosed
WO-2018134616-A1 METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2018-07-26 WO disclosed
US-20100190768-A1 NOVEL FUSED PYROLE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2010-07-29 US disclosed
CN-101321726-A Novel fused pyrrole derivative DAINIPPON SUMITOMO PHARMA CO (JP) 2008-12-10 CN disclosed
EP-1930320-A1 NOVEL FUSED PYRROLE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190768-A1 NOVEL FUSED PYROLE DERIVATIVE NR3C1, NR3C2, NR0B1 NPC1 4800/4885HSP90AA1 3432/4885RECQL 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.