Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 4/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 15/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598451 | 0.86 | ALDH1A1 (0.45) | NTSR1GRIN2B | |
| SCHEMBL3599421 | 0.84 | NTSR1 (0.56) | NTSR1GRIN2B | |
| SCHEMBL3594495 | 0.84 | GRIN2B (0.44) | NTSR1GRIN2B | |
| SCHEMBL3594446 | 0.83 | NTSR1 (0.47) | NTSR1GRIN2B | |
| SCHEMBL3600061 | 0.83 | GRIN2B (0.42) | NTSR1GRIN2B | |
| SCHEMBL3600784 | 0.83 | GRIN2B (0.48) | NTSR1GRIN2B | |
| SCHEMBL3598919 | 0.83 | HTR6 (0.47) | GRIN2B | |
| SCHEMBL3602467 | 0.82 | KDM4E (0.46) | GRIN2B | |
| SCHEMBL3597368 | 0.82 | TSHR (0.46) | GRIN2B | |
| SCHEMBL3600291 | 0.82 | GRIN2B (0.55) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807704-B2 | Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2 | CHEMOCENTRYX, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20070275965-A1 | CXCR4 modulators | CHEMOCENTRYX, INC. (US) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275965-A1 | CXCR4 modulators | CXCL12, CXCR4, CXCR1 | NTSR1 1072/4885GRIN2B 2950/4885METTL3 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.