Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369566 | 0.83 | GAA (0.39) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL3292786 | 0.83 | GAA (0.39) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL3292086 | 0.82 | GAA (0.41) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL3292077 | 0.82 | GAA (0.39) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL694106 | 0.81 | GAA (0.41) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL11374847 | 0.81 | GAA (0.44) | GAAALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11158747 | 0.81 | CASP1 (0.47) | GAAALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL13078771 | 0.80 | GAA (0.38) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL13328680 | 0.80 | GAA (0.37) | GAAKMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL10568525 | 0.80 | GAA (0.43) | GAAKMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AG (DE) | 2005-01-06 | — | — | US | disclosed |
| US-6838414-B2 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | GESING ERNST RUDOLF F (DE) | 2003-08-14 | — | — | US | disclosed |
| US-6451737-B1 | N-(4,6-DIMETHYL-PYRIMIDIN-2-YL)-N'-(2-METHOXY-6-TRIFLUOROMETHY L-PHENYLSULPHONYL)-UREA | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | TST, DDT, CBR3 | GAA 3660/4885KMT2A 2029/4885ATM 2611/4885 |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | DDT, CBR3, TST | GAA 3670/4885KMT2A 1518/4885ATM 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.