SCHEMBL360124

SCHEMBL360124

O=S(=O)(O)c1cc(CO)ccc1-c1ccc(CO)cc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.41
CA2 P00918 4/20 0.41
CA12 O43570 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
CA1 P00915 2/20 0.41
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
ESR2 Q92731 1/20 0.36
PTGES2 Q9H7Z7 3/20 0.36
ENPP2 Q13822 1/20 0.35
CA3 P07451 1/20 0.34
PDK2 Q15119 1/20 0.34
HSD17B10 Q99714 2/20 0.33
IKBKB O14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259655 0.82 EGFR (0.42) CHEK1CA2CA12CA4CA6
SCHEMBL361162 0.82 POLB (0.36) CA2CA12CA4CA9CA1
SCHEMBL1805735 0.80 POLB (0.55) CA2CA12CA4CA6CA5A
Hydrochloric Acid SCHEMBL28301073 0.79 PTGES2 (0.42) CA2CA12CA4CA6CA5A
SCHEMBL1802409 0.76 ESR2 (0.41) CA2CA12CA4CA6CA5A
SCHEMBL1806556 0.76 PTGES2 (0.40) CA2CA12CA4CA6CA5A
SCHEMBL2622534 0.76 CA1 (0.35) CA2CA1POLBRECQLESR2
SCHEMBL1807355 0.76 CDC25A (0.53) CA2CA5APOLBPTGES2LMNA
SCHEMBL361093 0.76 ESR2 (0.36) POLBRECQLESR2HSD17B10LMNA
SCHEMBL13665754 0.74 ALDH1A1 (0.42) CA2CA12CA4CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
EP-2638126-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX K.K. (JP) 2013-09-18 EP disclosed
EP-2630523-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX K.K. (JP) 2013-08-28 EP disclosed
EP-2622392-A1 PATTERNED RETARDER CRYSOPTIX K.K. (JP) 2013-08-07 EP disclosed
EP-2510396-A2 POLARIZER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX K.K. (JP) 2012-10-17 EP disclosed
WO-2012064618-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-18 WO disclosed
US-20120113380-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-10 US disclosed
US-20120099052-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 US disclosed
WO-2012052950-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-04-26 WO disclosed
WO-2012044867-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 WO disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
WO-2012008981-A2 POLARIZER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-01-19 WO disclosed
US-20110149206-A1 Polarizer and Liquid Crystal Display Comprising the Same CRYSOPTIX KK (JP) 2011-06-23 US disclosed