SCHEMBL361093

SCHEMBL361093

O=S(=O)(O)c1cc(CBr)ccc1-c1ccc(CBr)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.36
ESR1 P03372 1/20 0.36
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
GNG2 P59768 1/20 0.34
GNB1 P62873 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
PRKAB2 O43741 1/20 0.32
PRKAG1 P54619 1/20 0.32
PRKAA2 P54646 1/20 0.32
PRKAA1 Q13131 1/20 0.32
PRKAG3 Q9UGI9 1/20 0.32
PRKAG2 Q9UGJ0 1/20 0.32
PRKAB1 Q9Y478 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1458690 0.83 CES2 (0.41) CES2CES1TRPA1ALDH1A1TSHR
SCHEMBL360539 0.80 POLB (0.35) ESR2HSD17B10CES2CES1POLB
SCHEMBL2622534 0.79 CA1 (0.35) ESR2HSD17B10CYP1A2CYP2C9ALOX15
SCHEMBL27515175 0.79 GSTO1 (0.37) FOLH1ALDH1A1
SCHEMBL360124 0.76 CHEK1 (0.41) ESR2HSD17B10POLBRECQLLMNA
SCHEMBL2622526 0.74 BACE1 (0.43) ALOX15ALDH1A1
SCHEMBL2742903 0.73 S100A4 (0.42) HSD17B10CYP1A2CYP2C9ALOX15GNG2
SCHEMBL4549636 0.72 CA1 (0.37) ESR2POLBRECQLALDH1A1
Methane SCHEMBL27730661 0.71 HSD17B10 (0.36) HSD17B10CYP1A2CYP2C9ALOX15GNG2
SCHEMBL361162 0.71 POLB (0.36) ESR2HSD17B10POLBRECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
EP-2638126-B1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2015-02-18 EP disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
US-20140334002-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2014-11-13 US disclosed
EP-2638126-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX K.K. (JP) 2013-09-18 EP disclosed
EP-2630523-A1 RETARDER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX K.K. (JP) 2013-08-28 EP disclosed
WO-2012044867-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 WO disclosed
WO-2012044867-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 WO disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
US-20120081784-A1 PATTERNED RETARDER CRYSOPTIX KK (JP) 2012-04-05 US disclosed
WO-2012008981-A2 POLARIZER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-01-19 WO disclosed
WO-2012008981-A2 POLARIZER AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME CRYSOPTIX KK (JP) 2012-01-19 WO disclosed
US-20110149206-A1 Polarizer and Liquid Crystal Display Comprising the Same CRYSOPTIX KK (JP) 2011-06-23 US disclosed
US-20110149206-A1 Polarizer and Liquid Crystal Display Comprising the Same CRYSOPTIX KK (JP) 2011-06-23 US disclosed
US-20110149206-A1 Polarizer and Liquid Crystal Display Comprising the Same CRYSOPTIX KK (JP) 2011-06-23 US disclosed