Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608422 | 0.86 | NPSR1 (0.43) | MAPTALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL3613513 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL3597343 | 0.79 | HSD17B1 (0.59) | MAPT | |
| SCHEMBL3610616 | 0.77 | NPSR1 (0.48) | MAPTALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL3592991 | 0.76 | NPSR1 (0.40) | MAPTALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL12497225 | 0.76 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL3604669 | 0.73 | MAPK14 (0.65) | MAPTALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL3605885 | 0.73 | ESR1 (0.56) | MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL3605751 | 0.72 | SMN1; SMN2 (0.43) | MAPTALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL3607560 | 0.72 | PDE4D (0.44) | HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | MAPT 4883/4885ALDH1A1 4295/4885HPGD 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.