Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | STAT5B | P51692 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613039 | 0.89 | KDM4E (0.43) | MAPK14ALDH1A1HPGDLMNAABCC9 | |
| SCHEMBL3601335 | 0.87 | CSNK1D (0.47) | MAPK14ALDH1A1LMNAHIF1ANPSR1 | |
| SCHEMBL3609536 | 0.86 | OPRD1 (0.54) | MAPK14PTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL3604669 | 0.85 | MAPK14 (0.65) | MAPK14PTGS2PTGS1ALDH1A1HPGD | |
| SCHEMBL3599918 | 0.81 | MAPK14 (0.40) | MAPK14PTGS2ALDH1A1HPGDESR1 | |
| SCHEMBL3609477 | 0.80 | MAPK14 (0.58) | MAPK14PTGS2PTGS1ALDH1A1LMNA | |
| SCHEMBL3596790 | 0.79 | MAPT (0.44) | ALDH1A1HPGDLMNAHIF1ANPSR1 | |
| SCHEMBL3603091 | 0.79 | PTPN1 (0.45) | MAPK14ALDH1A1HPGDABCC9ABCC8 | |
| SCHEMBL3613774 | 0.78 | HSD11B1 (0.47) | ALDH1A1HPGDLMNAHIF1ANPSR1 | |
| SCHEMBL8985342 | 0.77 | MAPK14 (0.83) | MAPK14PTGS2PTGS1HPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | MAPK14 3384/4885PTGS2 2089/4885PTGS1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.