Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973163 | 0.81 | GAA (0.68) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL31717819 | 0.81 | GAA (0.68) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL31388416 | 0.81 | GAA (0.68) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL360193 | 0.81 | GAA (0.46) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL24603548 | 0.81 | SMN1; SMN2 (0.55) | GAAALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL10598844 | 0.78 | GAA (0.88) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL31132414 | 0.77 | SMN1; SMN2 (0.59) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8379624 | 0.77 | SMN1; SMN2 (0.59) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL359742 | 0.76 | GAA (0.41) | GAAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL14809676 | 0.72 | RAB9A (0.54) | GAAALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |