Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA12 | O43570 | 7/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360263 | 0.76 | RAB9A (0.55) | GAARAB9ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL360223 | 0.76 | GAA (0.68) | GAACA2RAB9ANPC1TYMS | |
| SCHEMBL14809676 | 0.71 | RAB9A (0.54) | GAARAB9ANPC1APOBEC3AAPOBEC3G | |
| SCHEMBL24603548 | 0.70 | SMN1; SMN2 (0.55) | GAARAB9ANPC1ALDH1A1TDP1 | |
| SCHEMBL360193 | 0.70 | GAA (0.46) | GAACA2TYMSALDH1A1CYP3A4 | |
| SCHEMBL359189 | 0.70 | HTT (0.54) | GAACA2CA12CA9CA1 | |
| SCHEMBL371310 | 0.69 | CA1 (0.42) | GAACA2CA12CA9CA1 | |
| SCHEMBL360852 | 0.67 | MAPT (0.58) | CA2CA12CA9CA1RAB9A | |
| SCHEMBL360416 | 0.67 | CA2 (0.41) | CA2CA12CA9CA1RAB9A | |
| SCHEMBL10713970 | 0.65 | TDP1 (0.46) | ALDH1A1CYP3A4TDP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |