Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24603548 | 0.81 | SMN1; SMN2 (0.55) | GAAKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL360223 | 0.81 | GAA (0.68) | GAAKMT2ATYMSTSHRALDH1A1 | |
| SCHEMBL14809676 | 0.74 | RAB9A (0.54) | GAAKMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL9306173 | 0.73 | ALDH1A1 (0.45) | GAAKMT2AMEN1MMP13ALDH1A1 | |
| SCHEMBL19709633 | 0.71 | ILK (0.40) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL617121 | 0.71 | RIPK1 (0.52) | KMT2AMEN1MMP13TSHRALDH1A1 | |
| SCHEMBL146922 | 0.71 | SMN1; SMN2 (0.67) | KMT2AMEN1MMP13TSHRALDH1A1 | |
| SCHEMBL359742 | 0.70 | GAA (0.41) | GAAKMT2AMEN1TYMSTSHR | |
| SCHEMBL31357824 | 0.70 | NQO2 (0.48) | KMT2AMEN1MMP13TSHRMAPK1 | |
| Water SCHEMBL27718168 | 0.70 | SMN1; SMN2 (0.65) | KMT2AMEN1MMP13TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |