Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590794 | 0.94 | KDM4E (0.35) | ALDH1A1PDE4BKDM4EPOLBCCR5 | |
| SCHEMBL3585659 | 0.89 | KMT2A (0.41) | ALDH1A1KDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL3592312 | 0.89 | MAPT (0.37) | ALDH1A1POLBCCR5SMN1; SMN2MEN1 | |
| SCHEMBL3599012 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBSMN1; SMN2KMT2A | |
| SCHEMBL3587526 | 0.87 | CCR5 (0.39) | ALDH1A1KDM4EPOLBCCR5MEN1 | |
| SCHEMBL3600445 | 0.86 | CCR5 (0.38) | ALDH1A1PDE4BPDE4DCCR5SMN1; SMN2 | |
| SCHEMBL3593561 | 0.86 | CCR5 (0.37) | PDE4BPDE4DPOLBCCR5SMN1; SMN2 | |
| SCHEMBL3597453 | 0.85 | POLB (0.35) | ALDH1A1POLBCCR5KMT2AMAPT | |
| SCHEMBL3585336 | 0.85 | ALDH1A1 (0.41) | ALDH1A1PDE4BPDE4DKDM4ECCR5 | |
| SCHEMBL3598302 | 0.85 | BCHE (0.36) | ALDH1A1KDM4EPOLBCCR5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190768-A1 | NOVEL FUSED PYROLE DERIVATIVE | NR3C1, NR3C2, NR0B1 | ALDH1A1 4118/4885PDE4B 1999/4885PDE4D 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.