Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834422 | 0.82 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTSMN1; SMN2DRD1 | |
| SCHEMBL10458167 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL3808547 | 0.80 | KMT2A (0.41) | ALDH1A1HPGDHTTSMN1; SMN2DRD1 | |
| SCHEMBL16178398 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2DRD1DRD2DRD4DRD5 | |
| SCHEMBL29922833 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL181586 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL29923063 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL5724553 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL4180652 | 0.76 | DRD1 (0.51) | ALDH1A1HPGDHTTSMN1; SMN2DRD1 | |
| SCHEMBL3214106 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022524-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022524-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | QTRT1, QTRT2, NQO2 | ALDH1A1 1420/4885HPGD 1019/4885HTT 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.