SCHEMBL181586

SCHEMBL181586

CCOc1cccc(C=O)c1OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
LMNA P02545 1/20 0.47
SRC P12931 1/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
GSK3A P49840 1/20 0.45
TLR2 O60603 1/20 0.44
ERN1 O75460 1/20 0.44
TLR1 Q15399 1/20 0.44
TLR6 Q9Y2C9 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922833 1.00 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL7494720 0.90 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL1253039 0.89 CA1 (0.54) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL1125257 0.89 SRC (0.58) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL28228828 0.88 LMNA (0.47) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL30485561 0.87 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL16161550 0.87 SMN1; SMN2 (0.49) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL7360395 0.87 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2HPGDHTTLMNA
SCHEMBL9248575 0.86 PTGDR2 (0.60) ALDH1A1SMN1; SMN2HPGDHTTSRC
SCHEMBL411835 0.86 HTR1A (0.56) ALDH1A1SMN1; SMN2HPGDHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11596716-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2023-03-07 US claimed
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US claimed
EP-3038621-A2 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR Human Biomolecular Research Institute (US) 2016-07-06 EP claimed
US-20160038641-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2016-02-11 US claimed
WO-2014146039-A2 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2014-09-18 WO claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed
CN-120504809-A High-air-permeability sponge foam material and preparation method thereof 东莞市腾崴塑胶制品有限公司 2025-08-19 CN disclosed
US-11596716-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2023-03-07 US disclosed
CN-113773202-B Polysubstituted phenanthrene compound, preparation method and application thereof 北京理工大学 2022-12-27 CN disclosed
CN-113773202-A Polysubstituted phenanthrene compound, preparation method and application thereof 北京理工大学 2021-12-10 CN disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US disclosed
CN-109438238-B Synthetic method of dihydrocinnamate compound 陕西师范大学 2021-04-13 CN disclosed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP disclosed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO disclosed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO disclosed
EP-0210140-B1 INHIBITORS OF BENZYLAMINOXIDASES, SELECTIVE WITH RESPECT TO OTHER AMINOXIDASES CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1990-06-13 EP disclosed
US-4888283-A Selective inhibitors of benzylaminoxidases with respect to other aminoxidases CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1989-12-19 US disclosed
EP-0210140-A2 Inhibitors of benzylaminoxidases, selective with respect to other aminoxidases CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1987-01-28 EP disclosed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596716-B2 Compounds and matrices for use in bone growth and repair BMP2, BMP4, BMP6 ALDH1A1 1413/4885SMN1; SMN2 3759/4885HPGD 291/4885
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR BMP2, BMP4, BMP6 ALDH1A1 1413/4885SMN1; SMN2 3759/4885HPGD 291/4885
US-20160038641-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR BMP2, BMP4, BMP6 ALDH1A1 1157/4885SMN1; SMN2 3375/4885HPGD 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.