Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 4/20 | 0.42 |
| ▸ | PTPRG | P23470 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610766 | 0.85 | TEAD2 (0.52) | SCD5GAAHTTKMT2ATSHR | |
| SCHEMBL6052401 | 0.83 | ALDH1A1 (0.56) | GAAKMT2AALDH1A1L3MBTL1KLKB1 | |
| SCHEMBL1047554 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL19779886 | 0.79 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL16246824 | 0.78 | KLKB1 (0.59) | HSD17B10KLKB1 | |
| SCHEMBL21523638 | 0.77 | KMT2A (0.49) | SCD5HTTKMT2ATSHRMAPK1 | |
| SCHEMBL21523737 | 0.75 | RAB9A (0.50) | SCD5HTTKMT2ATSHRMAPK1 | |
| SCHEMBL3599741 | 0.73 | KMT2A (0.52) | GAAHTTGFERKMT2ATSHR | |
| SCHEMBL14343418 | 0.73 | KLKB1 (0.53) | GAAKMT2ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL3657502 | 0.72 | EGLN1 (0.53) | KMT2ATSHRMAPK1HSD17B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | SCD5 4/4885GAA 411/4885HTT 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.