Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.46 |
| ▸ | WNT1 | P04628 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3609045 | 0.99 | F2 (0.46) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL3616757 | 0.90 | F2 (0.49) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL3602730 | 0.88 | RPS6KA2 (0.57) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL3602632 | 0.88 | SCD5 (0.51) | F2PLGPLAUPLATKLKB1 | |
| SCHEMBL13504884 | 0.85 | NAMPT (0.60) | RPS6KA2NAMPTRPS6KA3ALDH1A1 | |
| SCHEMBL13504959 | 0.85 | SCD5 (0.52) | RPS6KA2WNT1GSK3BDYRK1ANAMPT | |
| Hydrochloric Acid SCHEMBL3606790 | 0.84 | SCD5 (0.51) | RPS6KA2WNT1GSK3BDYRK1ANAMPT | |
| Hydrochloric Acid SCHEMBL3612494 | 0.84 | NAMPT (0.59) | RPS6KA2NAMPTRPS6KA3ALDH1A1 | |
| SCHEMBL3611274 | 0.82 | NAMPT (0.56) | NAMPT | |
| SCHEMBL3608690 | 0.81 | TAS2R8 (0.52) | RPS6KA2WNT1GSK3BDYRK1ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | F2 1314/4885PLG 3005/4885PLAU 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.