SCHEMBL3603458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3597094	0.91	PDE9A (0.64)	PDE9APDE5AFFAR4FFAR1FFAR2
	SCHEMBL13503596	0.83	PDE5A (0.39)	PDE9APDE5AKDM4EALDH1A1DAO
	SCHEMBL3599601	0.83	ADORA3 (0.43)	PDE9APDE5AFFAR1KMOGRIA1
	SCHEMBL3596260	0.82	PDE9A (0.63)	PDE9APDE5AFFAR4FFAR1FFAR2
	SCHEMBL3588994	0.81	PDE9A (0.59)	PDE9APDE5AFFAR1KMOKDM4E
	SCHEMBL3593767	0.79	PDE9A (0.50)	PDE9APDE5AGRIA1GRIA2GRIA3
	SCHEMBL3587991	0.76	PDE9A (0.47)	PDE9APDE5AFFAR1GRIA1GRIA2
	SCHEMBL3593369	0.75	PDE9A (0.60)	PDE9APDE5AFFAR4FFAR1FFAR2
	SCHEMBL3586843	0.75	PDE5A (0.52)	PDE9APDE5AGRIA1GRIA2GRIA3
	SCHEMBL3599313	0.74	PDE9A (0.51)	PDE9APDE5AGRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.