Uridine

Uridine

SCHEMBL360394

O=c1ccn(C2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 1.00
SLC28A2 O43868 1/20 1.00
SLC29A1 Q99808 1/20 1.00
SLC28A3 Q9HAS3 1/20 1.00
P2RY2 P41231 11/20 0.69
P2RY6 Q15077 8/20 0.65
P2RY4 P51582 4/20 0.63
P2RY14 Q15391 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL2114452 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL16273806 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL4455604 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2912983 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL890304 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL9945547 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056530 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056634 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20987631 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL8590899 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025080839-A1 IMPROVED RADIOSYNTHESIS OF 18F-LABELED NUCLEOSIDE ANALOGUES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-04-17 WO claimed
US-20230416293-A1 SYNTHESIS OF [18F]-LABELED THYMIDINE ANALOGUES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-12-28 US claimed
WO-2022109244-A1 SYNTHESIS OF [18F] -LABELED THYMIDINE ANALOGUES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2022-05-27 WO claimed
CN-105246337-B Thymidine Kinase Diagnostic Assays for Gene Therapy Applications 吉恩维沃公司 2019-02-15 CN claimed
EP-2603516-A2 SYNTHESIS OF 2'-DEOXY-2'-[18F]FLUORO-5-METHYL-1-B-D-ARABINOFURANOSYLURACIL (18F-FMAU) University of Southern California (US) 2013-06-19 EP claimed
WO-2012009666-A2 SYNTHESIS OF 2'-DEOXY-2'-[18F]FLUORO-5-METHYL-1-B-D-ARABINOFURANOSYLURACIL (18F-FMAU) UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-01-19 WO claimed
EP-1835035-B1 A process for immobilizing cells on a resin EXPLORA LAB SA (CH) 2010-02-17 EP claimed
EP-2009990-A2 METHODS AND COMPOSITIONS RELATED TO ADENOASSOCIATED VIRUS-PHAGE PARTICLES The Board of Regents of The University of Texas System (US) 2009-01-07 EP claimed
EP-1992632-A1 Method for the synthesis of cyclouridine EXPLORA Laboratories SA (CH) 2008-11-19 EP claimed
US-20070249023-A1 Process for immobilizing cells on a resin EXPLORA LABORATORIES S.A. (CH) 2007-10-25 US claimed
WO-2007118245-A2 METHODS AND COMPOSITIONS RELATED TO ADENOASSOCIATED VIRUS-PHAGE PARTICLES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-10-18 WO claimed
EP-1835035-A1 A process for immobilizing cells on a resin EXPLORA Laboratories SA (CH) 2007-09-19 EP claimed
WO-1996028190-A1 NON-INVASIVE IMAGING OF GENE TRANSFER SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-09-19 WO claimed
WO-2025080839-A1 IMPROVED RADIOSYNTHESIS OF 18F-LABELED NUCLEOSIDE ANALOGUES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-04-17 WO disclosed
CN-118837454-A Coronary atherosclerosis grading diagnosis biomarker based on plasma metabolome and application thereof 江南大学 2024-10-25 CN disclosed
CN-114630911-B Enzymatic process for the preparation of UDP-GlcNAc 马克斯·普朗克科学促进学会 2024-06-28 CN disclosed
WO-1990015064-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-13 WO disclosed
EP-0044085-B1 NOVEL NUCLEOSIDE DERIVATIVES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-05-25 EP disclosed
US-4367332-A N4 -Alkoxycarbonylarabinofuranosylcytosine ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-01-04 US disclosed
EP-0044085-A1 Novel nucleoside derivatives Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416293-A1 SYNTHESIS OF [18F]-LABELED THYMIDINE ANALOGUES DCTD, DUT, RNMT SLC28A1 33/4885SLC28A2 38/4885SLC29A1 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.