Uridine

Uridine

SCHEMBL890304

O=c1ccn([C@@H]2O[C@H](CO)C(O)C2O)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 1.00
SLC28A2 O43868 1/20 1.00
SLC29A1 Q99808 1/20 1.00
SLC28A3 Q9HAS3 1/20 1.00
P2RY2 P41231 11/20 0.69
P2RY6 Q15077 8/20 0.65
P2RY4 P51582 4/20 0.63
P2RY14 Q15391 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL2114452 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL360394 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL16273806 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL4455604 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2912983 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL9945547 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056530 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2056634 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL20987631 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL8590899 1.00 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255826-A Preparation method of 4' -azidopyrimidine nucleoside and analogue thereof 中国海洋大学 2024-06-28 CN disclosed
WO-2023283434-A9 AMINOOXY CLICK CHEMISTRY (AOCC): A VERSATILE BIOCONJUGATION APPROACH ALNYLAM PHARMACEUTICALS, INC. (US) 2024-03-28 WO disclosed
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 US disclosed
EP-4306646-A1 METHOD AND MEANS FOR SYNTHESIS OF C-NUCLEOSIDES OR C-NUCLEOTIDES Technische Universität Graz (AT) 2024-01-17 EP disclosed
WO-2024006953-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed
US-20230399354-A1 PREPARATION METHOD OF 2'-SUBSTITUTED PYRIMIDINE NUCLEOSIDE BEIJING RIBIO PHARMA CO., LTD. (CN) 2023-12-14 US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
WO-2023224108-A1 NUCLEOSIDE DERIVATIVE AND USE THEREOF 株式会社GF・Mille 2023-11-23 WO disclosed
WO-2023220440-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
WO-2023220428-A1 COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
US-7517990-B2 Method for deuteration of a heterocyclic ring WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-14 US disclosed
US-20090081686-A1 PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING AGILENT TECHNOLOGIES, INC. 2009-03-26 US disclosed
EP-1138775-B1 Method of preparing a guanosine-group compound and an intermediate thereof YUKI GOSEI YAKUHIN KOGYO KK (JP) 2008-12-03 EP disclosed
WO-2008142396-A1 METHODS OF ASSESSING MALE FERTILITY USING A URIDINE MARKER MAHER ANTHONY DENIS (GB) 2008-11-27 WO disclosed
EP-1947092-A1 NUCLEIC ACID BASE HAVING PERFLUOROALKYL GROUP AND METHOD FOR PRODUCING THE SAME Tosoh Corporation (JP) 2008-07-23 EP disclosed
US-7365178-B2 Acyl-nucleotide probes and methods of their synthesis and use in proteomic analysis ACTIVX BIOSCIENCES, INC. (US) 2008-04-29 US disclosed
US-20080064868-A1 Novel Dideoxynucleoside Derivatives WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-03-13 US disclosed
CN-1044911-C Process for preparing prodrug IGEN INC (US) 1999-09-01 CN disclosed
CN-1217335-A Method for preparing precursor medicine IGEN INC (US) 1999-05-26 CN disclosed
CN-1070409-A Prodrugs activated by targetted catalytic proteins IGEN INC (US) 1993-03-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 SLC28A1 545/4885SLC28A2 583/4885SLC29A1 216/4885
US-20080064868-A1 Novel Dideoxynucleoside Derivatives DNA2, DDX20, DNASE1 SLC28A1 373/4885SLC28A2 334/4885SLC29A1 150/4885
US-20230399354-A1 PREPARATION METHOD OF 2'-SUBSTITUTED PYRIMIDINE NUCLEOSIDE UMPS, TYMP, DPYD SLC28A1 81/4885SLC28A2 27/4885SLC29A1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.