SCHEMBL360448

SCHEMBL360448

C1=C(c2ccccc2)CCC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.47
SIGMAR1 Q99720 1/20 0.46
HTR2C P28335 1/20 0.45
PPARA Q07869 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PTGS2 P35354 1/20 0.40
MAT2A P31153 1/20 0.39
GRM2 Q14416 1/20 0.39
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6344544 0.95 ACMSD (0.49) ACMSDSIGMAR1HTR2CPPARATDP1
SCHEMBL8380044 0.92 ACMSD (0.49) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL191429 0.92 ACMSD (0.49) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL1109740 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL8356129 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL29094917 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL8360447 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL1109745 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL1094676 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2
SCHEMBL1109744 0.90 ACMSD (0.47) ACMSDSIGMAR1HTR2CTDP1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296528-A1 4-ARYL-1-(BIARYLMETHYLENE) PIPERIDINE COMPOUNDS KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY (SA) 2014-10-02 US claimed
EP-1767524-B1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AZIRIDINES AND AMINES, COMPLEXES USED IN THE PROCESS, AND INTERMEDIATES THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2013-05-22 EP claimed
US-20080081916-A1 Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-04-03 US claimed
EP-1767524-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE AZIRIDINES AND AMINES, COMPLEXES USED IN THE PROCESS, AND INTERMEDIATES THEREOF Japan Science and Technology Agency (JP) 2007-03-28 EP claimed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
US-12509418-B2 Chromophoric compounds and UV-absorbing compositions LYGG CORPORATION (US) 2025-12-30 US disclosed
CN-120736959-A Preparation method of odorant 3- (3-isopropylphenyl) butyraldehyde 杭州可菲克化学有限公司 2025-10-03 CN disclosed
US-20250270164-A1 CHROMOPHORIC COMPOUNDS AND UV-ABSORBING COMPOSITIONS LYGG CORPORATION 2025-08-28 US disclosed
US-20250263511-A1 COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOOLEFIN, PRODUCTION METHOD THEREFOR, RUBBER COMPOSITION, AND CROSSLINKED RUBBER OBJECT ZEON CORPORATION (JP) 2025-08-21 US disclosed
EP-0211447-B1 SCRUBBING OF GAS TO RECOVER HYDROCARBONS Linde Aktiengesellschaft (DE) 1991-12-04 EP disclosed
US-4918229-A Method of producing primary amines in high yields and novel intermediates therefor ALDRICH CHEMICAL COMPANY, INC. (US) 1990-04-17 US disclosed
US-4810267-A CARBOCYCLIC HYDROCARBON LINDE AKTIENGESELLSCHAFT (DE) 1989-03-07 US disclosed
US-4797140-A CARBOCYCLIC HYDROCARBONS AS A SCRUBBING MEDIUM LINDE AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
EP-0211447-A1 Scrubbing of gas to recover hydrocarbons Linde Aktiengesellschaft (DE) 1987-02-25 EP disclosed
US-4644075-A HYDROBORATION REAGENTS; ALDOL CONDENSATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1987-02-17 US disclosed
US-4291059-A 1-PHENYLCYCLOPENTANOL ACYLATE ESTER AND ITS PREPARATION GLAXO GROUP LIMITED (GB) 1981-09-22 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081916-A1 Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method INTS9, RAD54L, CD99 ACMSD 1234/4885SIGMAR1 331/4885HTR2C 498/4885
US-20250270164-A1 CHROMOPHORIC COMPOUNDS AND UV-ABSORBING COMPOSITIONS ERCC1, TYR, ERCC5 ACMSD 86/4885SIGMAR1 4530/4885HTR2C 462/4885
US-12509418-B2 Chromophoric compounds and UV-absorbing compositions LBR, ERCC1, MC1R ACMSD 530/4885SIGMAR1 473/4885HTR2C 658/4885
US-20140296528-A1 4-ARYL-1-(BIARYLMETHYLENE) PIPERIDINE COMPOUNDS HTR2C, HTR3C, HTR1D ACMSD 4033/4885SIGMAR1 39/4885HTR2C 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.