Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453783 | 0.85 | CES1 (0.55) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL238059 | 0.84 | CES1 (0.44) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL528366 | 0.82 | CES1 (0.52) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28013116 | 0.82 | CES1 (0.52) | CES1CES2ALDH1A1TSHRDAO | |
| Phosphine SCHEMBL28389655 | 0.82 | CES1 (0.52) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL1524419 | 0.82 | CES2 (0.46) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL7865764 | 0.82 | AKR1C3 (0.43) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL164078 | 0.82 | CES1 (0.42) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL28137597 | 0.82 | TDP1 (0.50) | CES1CES2ALDH1A1TSHRDAO | |
| SCHEMBL173454 | 0.79 | CES1 (0.39) | CES1CES2ALDH1A1TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2478021-B1 | Nitrile rubbers and production of same in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-11-04 | — | — | EP | claimed |
| CN-102498140-B | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2015-06-24 | — | — | CN | claimed |
| US-9023914-B2 | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-05 | — | — | US | claimed |
| CN-104185645-A | Process for producing nitrile rubber in organic solvent | LANXESS DEUTSCHLAND GMBH | 2014-12-03 | — | — | CN | claimed |
| US-20140235744-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-21 | — | — | US | claimed |
| EP-2739661-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS Deutschland GmbH (DE) | 2014-06-11 | — | — | EP | claimed |
| EP-2611843-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | claimed |
| CN-103080161-A | Method for producing nitrile rubbers in organic solvents | LANXESS DEUTSCHLAND GMBH | 2013-05-01 | — | — | CN | claimed |
| WO-2013017610-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-02-07 | — | — | WO | claimed |
| EP-2554558-A1 | Method for producing nitrile rubbers in organic solvents | Lanxess Deutschland GmbH (DE) | 2013-02-06 | — | — | EP | claimed |
| US-20120283351-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-11-08 | — | — | US | claimed |
| EP-2478021-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2012-07-25 | — | — | EP | claimed |
| CN-102498140-A | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2012-06-13 | — | — | CN | claimed |
| WO-2012028501-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | claimed |
| EP-2423238-A1 | Method for producing nitrile rubbers in organic solvents | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | claimed |
| EP-2385074-A1 | Nitrile rubbers and production of same in organic solvents | LANXESS Deutschland GmbH (DE) | 2011-11-09 | — | — | EP | claimed |
| US-8038675-B2 | Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm | ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) | 2011-10-18 | — | — | US | claimed |
| WO-2011032832-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-03-24 | — | — | WO | claimed |
| EP-2298824-A1 | Nitrile rubbers and production of same in organic solvents | LANXESS Deutschland GmbH (DE) | 2011-03-23 | — | — | EP | claimed |
| US-10906997-B2 | Crosslinker-accelerator system for polyacrylates | TESA SE (DE) | 2021-02-02 | — | — | US | disclosed |
| US-10858455-B2 | Process for the production of water and solvent-free nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2020-12-08 | — | — | US | disclosed |
| US-20180155468-A1 | CROSSLINKER-ACCELERATOR SYSTEM FOR POLYACRYLATES | TESA SE (DE) | 2018-06-07 | — | — | US | disclosed |
| US-9896521-B2 | Crosslinker-accelerator system for polyacrylates | TESA SE (DE) | 2018-02-20 | — | — | US | disclosed |
| EP-2186869-B2 | Thermally interlinking polyacrylate and method for its manufacture | TESA SE (DE) | 2017-10-04 | — | — | EP | disclosed |
| CN-103275337-B | Cross-linking agent-accelerator system for polyacrylate | 德莎欧洲公司 | 2016-12-28 | — | — | CN | disclosed |
| US-20160369014-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-9505959-B2 | Thermally crosslinking polyacrylates and process for their preparation | TESA SE (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9469697-B2 | Process for the production of water and solvent-free nitrile rubbers | LANXESS DEUTSCHLAND GMBH (DE) | 2016-10-18 | — | — | US | disclosed |
| EP-2478021-B1 | Nitrile rubbers and production of same in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-11-04 | — | — | EP | disclosed |
| CN-102498140-B | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2015-06-24 | — | — | CN | disclosed |
| US-20150148444-A1 | PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM | TESA SE (DE) | 2015-05-28 | — | — | US | disclosed |
| US-9023914-B2 | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-8969479-B2 | Pressure-sensitive adhesives and process for preparing them | TESA SE (DE) | 2015-03-03 | — | — | US | disclosed |
| CN-104211859-A | Nitrile rubbers coupled via bisdihydropyrazole groups, production thereof and use thereof | LANXESS DEUTSCHLAND GMBH | 2014-12-17 | — | — | CN | disclosed |
| EP-2810957-A1 | Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same | LANXESS Deutschland GmbH (DE) | 2014-12-10 | — | — | EP | disclosed |
| EP-2810956-A1 | Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same | LANXESS Deutschland GmbH (DE) | 2014-12-10 | — | — | EP | disclosed |
| US-20140357801-A1 | Nitrile rubbers coupled via bisdihydropyrazole groups, production thereof and use thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| CN-104185645-A | Process for producing nitrile rubber in organic solvent | LANXESS DEUTSCHLAND GMBH | 2014-12-03 | — | — | CN | disclosed |
| US-20140329982-A1 | METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-11-06 | — | — | US | disclosed |
| EP-2798001-A1 | METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS | LANXESS Deutschland GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| CN-102822205-B | Process for the production of water and solvent free nitrile rubbers | LANXESS INT SA | 2014-09-24 | — | — | CN | disclosed |
| EP-2617788-B1 | Crosslinking accelerator system for polyacrylates | TESA SE (DE) | 2014-09-03 | — | — | EP | disclosed |
| CN-104024322-A | Process for producing purified nitrile rubber | LANXESS DEUTSCHLAND GMBH | 2014-09-03 | — | — | CN | disclosed |
| US-20140235744-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2014-08-21 | — | — | US | disclosed |
| US-8802777-B2 | Thermally crosslinking polyacrylates and method for producing the same | TESA SE (DE) | 2014-08-12 | — | — | US | disclosed |
| US-20140170326-A1 | Thermally Crosslinking Polyacrylates and Process for their Preparation | TESA SE (DE) | 2014-06-19 | — | — | US | disclosed |
| EP-2739661-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS Deutschland GmbH (DE) | 2014-06-11 | — | — | EP | disclosed |
| CN-101724173-B | Thermally interlinking polyacrylate and method for its manufacture | TESA SE | 2013-10-16 | — | — | CN | disclosed |
| CN-103275337-A | Crosslinking accelerator system for polyacrylates | TESA SE | 2013-09-04 | — | — | CN | disclosed |
| US-20130211031-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | LANXESS International S.A. (CH) | 2013-08-15 | — | — | US | disclosed |
| EP-2623518-A1 | Nitrile rubbers coupled with bistriazolyl groups, production and use of same | Lanxess Deutschland GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| CN-101735467-B | Thermally crosslinking polyacrylates and process for their preparation | TESA SE | 2013-08-07 | — | — | CN | disclosed |
| US-20130190459-A1 | CROSSLINKER-ACCELERATOR SYSTEM FOR POLYACRYLATES | TESA SE (DE) | 2013-07-25 | — | — | US | disclosed |
| EP-2617788-A1 | Crosslinking accelerator system for polyacrylates | tesa SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2611843-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| EP-2611836-A1 | RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS | Lanxess Deutschland GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| WO-2013098073-A1 | METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610296-A1 | Method for production of purified nitrile rubbers | Lanxess Deutschland GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| CN-103080161-A | Method for producing nitrile rubbers in organic solvents | LANXESS DEUTSCHLAND GMBH | 2013-05-01 | — | — | CN | disclosed |
| CN-103080138-A | Rubber blend consisting of different nitrile rubbers | LANXESS DEUTSCHLAND GMBH | 2013-05-01 | — | — | CN | disclosed |
| WO-2013017610-A1 | PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2013-02-07 | — | — | WO | disclosed |
| EP-2554558-A1 | Method for producing nitrile rubbers in organic solvents | Lanxess Deutschland GmbH (DE) | 2013-02-06 | — | — | EP | disclosed |
| EP-2550301-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | Lanxess Deutschland GmbH (DE) | 2013-01-30 | — | — | EP | disclosed |
| CN-102822205-A | Process for the production of water and solvent free nitrile rubbers | LANXESS INT SA | 2012-12-12 | — | — | CN | disclosed |
| US-20120283351-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-11-08 | — | — | US | disclosed |
| EP-2192148-B1 | Thermally crosslinking polyacrylates and method for their manufacture | TESA SE (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2368916-B1 | Process for the production of water and solvent-free nitrile rubbers | LANXESS INT SA (CH) | 2012-08-22 | — | — | EP | disclosed |
| EP-2478021-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | Lanxess Deutschland GmbH (DE) | 2012-07-25 | — | — | EP | disclosed |
| CN-101679822-B | Thermally crosslinked polyacrylates and process for their preparation | TESA SE | 2012-07-18 | — | — | CN | disclosed |
| EP-2186869-B1 | Thermally interlinking polyacrylate and method for its manufacture | TESA SE (DE) | 2012-06-27 | — | — | EP | disclosed |
| CN-102498140-A | Nitrile rubbers and production thereof in organic solvents | LANXESS DEUTSCHLAND GMBH | 2012-06-13 | — | — | CN | disclosed |
| WO-2012028501-A1 | METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012028506-A1 | RUBBER BLENDS CONSISTING OF DIFFERENT NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2423238-A1 | Method for producing nitrile rubbers in organic solvents | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2423234-A1 | Rubber blends from different nitrile rubbers | LANXESS Deutschland GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20110274843-A1 | Thermally Crosslinking Polyacrylates And Process For Their Preparation | TESA AKTIENGESELLSCHAFT (DE) | 2011-11-10 | — | — | US | disclosed |
| EP-2385074-A1 | Nitrile rubbers and production of same in organic solvents | LANXESS Deutschland GmbH (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-8038675-B2 | Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm | ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011117194-A1 | PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368916-A1 | Process for the production of water and solvent-free nitrile rubbers | LANXESS International SA (CH) | 2011-09-28 | — | — | EP | disclosed |
| EP-2143773-B1 | Adhesive masses and method for their manufacture | TESA SE (DE) | 2011-04-27 | — | — | EP | disclosed |
| WO-2011032832-A1 | NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |
| EP-2298824-A1 | Nitrile rubbers and production of same in organic solvents | LANXESS Deutschland GmbH (DE) | 2011-03-23 | — | — | EP | disclosed |
| CN-101735467-A | Thermally crosslinking polyacrylates and process for their preparation | TESA SE | 2010-06-16 | — | — | CN | disclosed |
| CN-101724173-A | Thermally interlinking polyacrylate and method for its manufacture | TESA SE | 2010-06-09 | — | — | CN | disclosed |
| US-20100137524-A1 | Thermally Crosslinking Polyacrylates And Process For Their Preparation | TESA SE (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-2192148-A1 | Thermally crosslinking polyacrylates and method for their manufacture | tesa AG (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-1978069-B1 | THERMALLY CROSSLINKING POLYACRYLATE AND METHOD FOR ITS MANUFACTURE | TESA SE (DE) | 2010-05-19 | — | — | EP | disclosed |
| EP-2186869-A1 | Thermally interlinking polyacrylate and method for its manufacture | tesa SE (DE) | 2010-05-19 | — | — | EP | disclosed |
| US-20100104864-A1 | THERMALLY CROSSLINKING POLYACRYLATES AND METHOD FOR PRODUCING THE SAME | TESA SE (DE) | 2010-04-29 | — | — | US | disclosed |
| CN-101679822-A | Thermally crosslinked polyacrylates and process for their preparation | TESA AG | 2010-03-24 | — | — | CN | disclosed |
| US-20100010112-A1 | PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM | TESA AG (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2143773-A1 | Adhesive masses and method for their manufacture | tesa SE (DE) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008122489-A1 | THERMALLY CROSSLINKING POLYACRYLATES AND METHOD FOR PRODUCING THE SAME | TESA SE (DE) | 2008-10-16 | — | — | WO | disclosed |
| EP-1978069-A1 | Thermally interlinking polyacrylate and method for its manufacture | Tesa AG (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1978069-A1 | Thermally interlinking polyacrylate and method for its manufacture | Tesa AG (DE) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357801-A1 | Nitrile rubbers coupled via bisdihydropyrazole groups, production thereof and use thereof | CYP2E1, NOS3, NOS2 | CES1 349/4885CES2 107/4885ALDH1A1 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.