Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599801 | 0.88 | ATAD2 (0.68) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL12991995 | 0.85 | ATAD2 (0.60) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL12991396 | 0.85 | ATAD2 (0.52) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL3605571 | 0.82 | CHRM1 (0.40) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL10130299 | 0.82 | GRIN1 (0.46) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL12992127 | 0.81 | ATAD2 (0.77) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8265234 | 0.79 | ATAD2 (0.50) | ATAD2CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL10160254 | 0.79 | ATAD2 (0.52) | ATAD2CHRM1BRD4HSD17B3POLB | |
| SCHEMBL14277003 | 0.78 | POLB (0.61) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL31419471 | 0.77 | ATAD2 (0.50) | ATAD2DRD2DRD4DRD3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2128157-A1 | HETEROCYCLIDENE-N-(ARYL)ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | ATAD2 1819/4885CHRM1 94/4885CHRM2 110/4885 |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | TRPV1, TRPV2, TRPV5 | ATAD2 231/4885CHRM1 911/4885CHRM2 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.