Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.39 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595932 | 0.88 | DPP4 (0.49) | DPP4DPP8QPCTMEN1KMT2A | |
| SCHEMBL3091375 | 0.86 | DPP4 (0.47) | DPP4DPP8 | |
| SCHEMBL3102277 | 0.84 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3091436 | 0.84 | DPP4 (0.46) | DPP4DPP8MEN1KMT2A | |
| SCHEMBL3091438 | 0.84 | CXCR2 (0.51) | DPP4YTHDC1DPP8BCL2L2 | |
| SCHEMBL3596602 | 0.84 | TTR (0.40) | DPP4TTRYTHDC1S1PR1S1PR5 | |
| SCHEMBL3089977 | 0.83 | BCL2L2 (0.50) | DPP4YTHDC1DPP8BCL2L2 | |
| SCHEMBL3089796 | 0.82 | DPP4 (0.44) | DPP4DPP8QPCTQPCTL | |
| SCHEMBL3595741 | 0.82 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3096840 | 0.82 | DPP4 (0.46) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |